Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005581 | 0.86 | PNMT (0.58) | PPARGPPARDPPARATBXAS1 | |
| SCHEMBL5130053 | 0.86 | PNMT (0.58) | PPARGPPARDPPARATBXAS1 | |
| SCHEMBL6003855 | 0.86 | PNMT (0.58) | PPARGPPARDPPARATBXAS1 | |
| SCHEMBL17414653 | 0.84 | KDM6B (0.66) | KDM6BOPRK1ALOX15KDM4ERECQL | |
| SCHEMBL1755353 | 0.84 | KDM6B (0.66) | KDM6BOPRK1ALOX15KDM4ERECQL | |
| SCHEMBL17211513 | 0.84 | KDM6B (0.66) | KDM6BOPRK1ALOX15KDM4ERECQL | |
| SCHEMBL30388652 | 0.84 | KDM6B (0.66) | KDM6BOPRK1ALOX15KDM4ERECQL | |
| Water SCHEMBL7451516 | 0.83 | KDM6B (0.64) | KDM6BOPRK1ALOX15KDM4ERECQL | |
| SCHEMBL2434639 | 0.81 | CA2 (0.47) | CA2CA1OPRK1ALOX15KDM4E | |
| SCHEMBL13604872 | 0.81 | ESR1 (0.53) | KDM6BOPRK1ALOX15KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216529-A1 | β-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | TREVENA, INC. (US) | 2021-10-28 | — | — | WO | disclosed |