Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954077 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TP53RAB9ASMN1; SMN2TSHR | |
| SCHEMBL18712125 | 0.80 | MEN1 (0.38) | ALDH1A1TP53HSD17B10MEN1KMT2A | |
| SCHEMBL17089325 | 0.80 | CA1 (0.55) | ALDH1A1TP53RAB9ASMN1; SMN2TSHR | |
| SCHEMBL16955522 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TP53RAB9ASMN1; SMN2TSHR | |
| SCHEMBL2667962 | 0.78 | RECQL (0.49) | ALDH1A1TP53SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL24840515 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2TDP1KMT2AKDM4E | |
| SCHEMBL8861494 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TP53RAB9ASMN1; SMN2TSHR | |
| SCHEMBL4206265 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TP53RAB9ASMN1; SMN2TSHR | |
| SCHEMBL363918 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TP53RAB9ASMN1; SMN2TSHR | |
| SCHEMBL29518159 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TP53RAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903583-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS III | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |
| EP-3903582-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |