SCHEMBL4206265

SCHEMBL4206265

C=C(C)c1cc(Cl)ccc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TP53 P04637 3/20 0.54
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
TSHR P16473 3/20 0.44
HSD17B10 Q99714 3/20 0.44
CYP3A4 P08684 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 2/20 0.43
ALOX15 P16050 1/20 0.43
CYP1A2 P05177 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C19 P33261 1/20 0.43
KDM4E B2RXH2 2/20 0.43
ERCC5 P28715 1/20 0.43
FEN1 P39748 1/20 0.43
MAPT P10636 1/20 0.40
GABRA1 P14867 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13689698 0.82 MEN1 (0.59) ALDH1A1TP53RAB9ASMN1; SMN2TSHR
SCHEMBL16954077 0.81 ALDH1A1 (0.58) ALDH1A1TP53RAB9ASMN1; SMN2TSHR
SCHEMBL28409813 0.81 ALDH1A1 (0.39) ALDH1A1TP53RAB9ASMN1; SMN2TSHR
SCHEMBL20076688 0.80 GABRA1 (0.41) ALDH1A1TP53RAB9ATDP1MEN1
SCHEMBL23128682 0.80 CYP3A4 (0.45) ALDH1A1TP53HSD17B10CYP3A4MEN1
SCHEMBL14364717 0.80 CA1 (0.55) ALDH1A1TP53RAB9ASMN1; SMN2TSHR
SCHEMBL16955522 0.79 ALDH1A1 (0.61) ALDH1A1TP53RAB9ASMN1; SMN2TSHR
SCHEMBL16174408 0.78 F2R (0.38) ALDH1A1TP53RAB9ASMN1; SMN2TSHR
SCHEMBL13689798 0.78 CYP3A4 (0.48) ALDH1A1RAB9ATSHRHSD17B10CYP3A4
SCHEMBL28966738 0.78 MEN1 (0.37) ALDH1A1TP53RAB9ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0030716-B1 CHLORINATED PVC BLENDS WITH IMPROVED PROCESSABILITY The B.F. GOODRICH Company (US) 1984-02-08 EP claimed
EP-4000606-A1 COMPOUNDS FOR CORONAVIRUS INFECTION TREATMENT AND/OR PREVENTION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-05-25 EP disclosed
US-8822592-B2 Aqueous emulsion polymer as dispersant BASF SE (DE) 2014-09-02 US disclosed
US-20090234062-A1 Aqueous emulsion polymer as dispersant CIBA SPECIALTY CHEMICALS CORP. 2009-09-17 US disclosed
EP-1444302-B1 LEVELLING AGENT AND ANTI-CRATERING AGENT CIBA HOLDING INC (CH) 2009-06-17 EP disclosed
US-7173084-B2 Levelling agent and anti-cratering agent EFKA ADDITIVES B.V. (NL) 2007-02-06 US disclosed
EP-1562696-B1 AQUEOUS EMULSION POLYMER AS DISPERSANT CIBA SC HOLDING AG (CH) 2006-03-29 EP disclosed
EP-1562696-A2 AQUEOUS EMULSION POLYMER AS DISPERSANT Efka Additives B.V. (NL) 2005-08-17 EP disclosed
US-20040236007-A1 Levelling agent and anti-cratering agent CIBA SPECIALTY CHEMICALS CORPORATION 2004-11-25 US disclosed
EP-1444302-A1 LEVELLING AGENT AND ANTI-CRATERING AGENT Efka Additives B.V. (NL) 2004-08-11 EP disclosed
WO-2004045755-A2 AQUEOUS EMULSION POLYMER AS DISPERSANT EFKA ADDITIVES B.V. (NL) 2004-06-03 WO disclosed
WO-2003033603-A1 LEVELLING AGENT AND ANTI-CRATERING AGENT EFKA ADDITIVES B.V. (NL) 2003-04-24 WO disclosed
EP-0030716-B1 CHLORINATED PVC BLENDS WITH IMPROVED PROCESSABILITY The B.F. GOODRICH Company (US) 1984-02-08 EP disclosed
US-4304884-A A-ALKYLSTYRENE-VINYLBENZENE OR ACRYLATE-NITRILE TERPOLYMER THE B. F. GOODRICH COMPANY (US) 1981-12-08 US disclosed
EP-0030716-A1 Chlorinated PVC blends with improved processability The B.F. GOODRICH Company (US) 1981-06-24 EP disclosed
US-4085165-A ISOCYANATE PREPOLYMER, VINYL COMPOUND, POLYAMINE OR POLYETHER CURING AGENT BRIDGESTONE TIRE CO., LTD. (JA) 1978-04-18 US disclosed
US-4075237-A Perfluorinated esters of fumaric acid and certain other ethylenically unsaturated poly-basic acid and soil repellant polymers thereof GEIGY CHEMICAL CORPORATION (US) 1978-02-21 US disclosed
US-3949136-A OIL REPELLENTS, WATERPROOFING TEXTILES CIBA-GEIGY AG (CH) 1976-04-06 US disclosed