Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.57 |
| ▸ | RAB9A | P51151 | 12/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18344133 | 0.90 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL18344170 | 0.90 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL1096066 | 0.85 | RAB9A (0.69) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1096844 | 0.85 | RAB9A (0.69) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1096068 | 0.85 | RAB9A (0.69) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL19326470 | 0.82 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL18344077 | 0.82 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL23965745 | 0.80 | SMN1; SMN2 (0.60) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL1094011 | 0.78 | HRH3 (0.61) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL1094008 | 0.78 | HRH3 (0.61) | NPC1RAB9ASMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | FUJIFILM CORPORATION (JP) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | HAVCR2, HBS1L, PHKB | NPC1 1739/4885RAB9A 2878/4885SMN1; SMN2 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.