Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 14/20 | 0.84 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966848 | 0.92 | S1PR2 (0.72) | S1PR2RHEBNLRP3TSHR | |
| SCHEMBL23966844 | 0.91 | S1PR2 (0.70) | S1PR2RHEBNLRP3 | |
| SCHEMBL23908918 | 0.90 | S1PR2 (0.69) | S1PR2AKR1B1RHEBNLRP3 | |
| SCHEMBL23914869 | 0.89 | S1PR2 (0.72) | S1PR2RHEBNPC1RAB9A | |
| SCHEMBL23914868 | 0.88 | S1PR2 (0.66) | S1PR2AKR1B1NLRP3TSHR | |
| SCHEMBL23914638 | 0.88 | S1PR2 (0.80) | S1PR2RHEBTSHR | |
| SCHEMBL23908887 | 0.88 | S1PR2 (0.94) | S1PR2AKR1B1TSHR | |
| SCHEMBL23908858 | 0.85 | S1PR2 (0.75) | S1PR2TSHR | |
| SCHEMBL23908839 | 0.84 | S1PR2 (0.75) | S1PR2RHEB | |
| SCHEMBL23908998 | 0.82 | S1PR2 (0.83) | S1PR2AKR1B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |