Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 11/20 | 0.72 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966844 | 0.93 | S1PR2 (0.70) | S1PR2NLRP3RHEB | |
| SCHEMBL23966552 | 0.92 | S1PR2 (0.84) | S1PR2NLRP3RHEBTSHR | |
| SCHEMBL23908918 | 0.92 | S1PR2 (0.69) | S1PR2NLRP3RHEBPTGES | |
| SCHEMBL23914869 | 0.86 | S1PR2 (0.72) | S1PR2RHEBTP53 | |
| SCHEMBL23966818 | 0.85 | S1PR2 (0.65) | S1PR2RHEBEGFRTP53 | |
| SCHEMBL23914868 | 0.81 | S1PR2 (0.66) | S1PR2NLRP3TSHR | |
| SCHEMBL23914638 | 0.81 | S1PR2 (0.80) | S1PR2RHEBTSHR | |
| SCHEMBL23966531 | 0.81 | S1PR2 (0.87) | S1PR2TP53TSHRPOLB | |
| SCHEMBL23914694 | 0.81 | S1PR2 (0.76) | S1PR2TP53TSHRPOLB | |
| SCHEMBL23908887 | 0.80 | S1PR2 (0.94) | S1PR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |