Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.46 |
| ▸ | HTR2A | P28223 | 11/20 | 0.46 |
| ▸ | HTR2C | P28335 | 9/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23914917 | 0.87 | NPC1 (0.54) | SLC6A4HTR2AHTR2CRECQLLMNA | |
| SCHEMBL23966582 | 0.80 | SLC6A4 (0.48) | SLC6A4HTR2AHTR2CRECQL | |
| SCHEMBL23915630 | 0.77 | MAPT (0.54) | SLC6A4HTR2AHTR2CLMNAGAA | |
| SCHEMBL23915510 | 0.75 | S1PR2 (0.58) | RECQLLMNAGAATSHRMAPK1 | |
| SCHEMBL23966572 | 0.75 | RECQL (0.57) | RECQLLMNAGAATSHRMAPK1 | |
| SCHEMBL9529811 | 0.75 | RECQL (0.62) | RECQLLMNAGAATSHRMAPK1 | |
| SCHEMBL23966843 | 0.75 | ALOX15 (0.51) | SLC6A4HTR2AHTR2CLMNASMN1; SMN2 | |
| SCHEMBL23909042 | 0.73 | TSHR (0.55) | RECQLTSHRSMN1; SMN2 | |
| SCHEMBL23915394 | 0.72 | RECQL (0.56) | RECQLTSHRSMN1; SMN2 | |
| SCHEMBL23915389 | 0.71 | RECQL (0.52) | RECQLLMNAGAATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |