Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 3/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783040 | 0.91 | SRC (0.55) | SIGMAR1HRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL4429202 | 0.91 | SRC (0.55) | SIGMAR1HRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL4690065 | 0.84 | KDM4E (0.54) | ALDH1A1ACHESRCFGFR1CHEK1 | |
| SCHEMBL3351733 | 0.81 | SRC (0.58) | SIGMAR1HRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL31061228 | 0.81 | ALDH1A1 (0.51) | SIGMAR1HRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3351728 | 0.81 | ALDH1A1 (0.51) | SIGMAR1HRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL28969386 | 0.81 | SRC (0.50) | HRH3KCNH2SRCFGFR1KDR | |
| SCHEMBL31491127 | 0.79 | SRC (0.53) | HRH3KCNH2SRCFGFR1KDR | |
| SCHEMBL30486269 | 0.79 | MAP4K4 (0.51) | SIGMAR1HRH3ACHE | |
| SCHEMBL4416637 | 0.79 | MAP4K4 (0.51) | SIGMAR1HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978513-A | Gefitinib-linked triazole derivative and preparation method and application thereof | 河南师范大学 | 2024-11-19 | — | — | CN | disclosed |
| US-9579365-B2 | Therapeutic ribonucleases | QUINTESSENCE BIOSCIENCES, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-20150209415-A1 | THERAPEUTIC RIBONUCLEASES | QUINTESSENCE BIOSCIENCES, INC. | 2015-07-30 | — | — | US | disclosed |
| EP-2670775-A1 | ANTI-TACE ANTIBODY MOLECULES AND THEIR USES | Cancer Research Technology Limited (GB) | 2013-12-11 | — | — | EP | disclosed |
| WO-2012104581-A1 | ANTI-TACE ANTIBODY MOLECULES AND THEIR USES | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2012-08-09 | — | — | WO | disclosed |
| US-8216567-B2 | Therapeutic ribonucleases | QUINTESSENCE BIOSCIENCES, INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-20120003150-A1 | THERAPEUTIC RIBONUCLEASES | QUINTESSENCE BIOSCIENCES, INC. (US) | 2012-01-05 | — | — | US | disclosed |