Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239668 | 0.81 | SIGMAR1 (0.56) | SRCALDH1A1KDRCYP1A2USP2 | |
| SCHEMBL7763005 | 0.80 | EGFR (0.61) | SRCKDRKCNH2HRH3EGFR | |
| SCHEMBL12474209 | 0.80 | EGFR (0.55) | SRCKDRKCNH2HRH3EGFR | |
| SCHEMBL31331907 | 0.79 | EGFR (0.65) | SRCKDRKCNH2HRH3EGFR | |
| SCHEMBL7766288 | 0.78 | EGFR (0.73) | SRCKDRKCNH2HRH3EGFR | |
| SCHEMBL31385612 | 0.75 | MEN1 (0.53) | ALDH1A1CYP1A2SIGMAR1CHRM2CHRM1 | |
| SCHEMBL12694372 | 0.75 | AURKA (0.74) | SRCALDH1A1KDREGFRILK | |
| SCHEMBL4759642 | 0.75 | SRC (0.60) | SRCALDH1A1KDRCYP1A2USP2 | |
| SCHEMBL30783040 | 0.74 | SRC (0.55) | SRCALDH1A1KDRCYP1A2USP2 | |
| SCHEMBL4429202 | 0.74 | SRC (0.55) | SRCALDH1A1KDRCYP1A2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090661-A9 | 6.7-DIALKOXY OUINAZOLINE DERIVATIVES USEFUL FOR TREATMENT OF CANCER RELATED DISORDERS | NATCO PHARMA LIMITED (IN) | 2010-06-17 | — | — | WO | disclosed |