Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527137 | 0.69 | — | — | |
| SCHEMBL23914731 | 0.59 | ALDH1A1 (0.55) | MEN1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL4764335 | 0.58 | DYRK1A (0.44) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL11967669 | 0.57 | PRKCA (0.30) | — | |
| SCHEMBL2992690 | 0.57 | PRKCA (0.30) | — | |
| SCHEMBL1252076 | 0.57 | ALDH1A1 (0.46) | MEN1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1252074 | 0.57 | ALDH1A1 (0.46) | MEN1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL9173461 | 0.56 | — | — | |
| SCHEMBL16976452 | 0.56 | MAPT (0.44) | MEN1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL17993974 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |