Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23967350 | 0.86 | KDM4E (0.52) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL30873583 | 0.86 | KDM4E (0.52) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL30873584 | 0.86 | KDM4E (0.52) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL555269 | 0.83 | KDM4E (0.64) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Dimethylamine SCHEMBL11757110 | 0.82 | TSHR (0.61) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL9651440 | 0.82 | SMN1; SMN2 (0.64) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL9856486 | 0.81 | HSD17B10 (0.65) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL11985691 | 0.81 | PTGS2 (0.68) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL2600810 | 0.81 | PTGS2 (0.56) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL8587601 | 0.80 | KDM4E (0.63) | KDM4EHSD17B10LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677660-A | Acetylsalicylic acid derivative and application thereof | 张婧 | 2021-11-19 | — | — | CN | claimed |
| US-20210387950-A1 | ACETYLSALICYLIC ACID DERIVATIVE AND APPLICATION THEREOF | ZHEJIANG HANMAI PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2021-12-16 | — | — | US | disclosed |
| CN-113677660-A | Acetylsalicylic acid derivative and application thereof | 张婧 | 2021-11-19 | — | — | CN | disclosed |
| EP-3904335-A1 | ACETYLSALICYLIC ACID DERIVATIVE AND APPLICATION THEREOF | Zhang, Jing (CN) | 2021-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387950-A1 | ACETYLSALICYLIC ACID DERIVATIVE AND APPLICATION THEREOF | PTGS1, PTGIS, PTGS2 | KDM4E 4300/4885HSD17B10 616/4885LMNA 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.