SCHEMBL23967645

SCHEMBL23967645

CSc1ccc(N(I)c2ccc(C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
TSHR P16473 2/20 0.46
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 3/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SLC6A4 P31645 5/20 0.41
NOX1 Q9Y5S8 1/20 0.41
ALOX12 P18054 1/20 0.41
QPCT Q16769 1/20 0.38
EGFR P00533 2/20 0.38
PDGFRB P09619 2/20 0.38
KDR P35968 2/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A3 Q01959 1/20 0.37
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650369 0.83 ALDH1A1 (0.63) ALDH1A1TSHRMAPTRAB9AALOX12
SCHEMBL21183244 0.82 MEN1 (0.46) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL76792 0.81
Water SCHEMBL27813433 0.78 MEN1 (0.54) ALDH1A1TSHRMEN1KMT2AMAPT
Hydrochloric Acid SCHEMBL7990919 0.78 MEN1 (0.54) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL23051049 0.78 ALDH1A1 (0.40) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL12533886 0.77 MEN1 (0.42) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL24134022 0.77 ALDH1A1 (0.44) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL77289 0.74 NOX1 (0.62) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL8736741 0.74 MEN1 (0.50) ALDH1A1TSHRMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed