SCHEMBL23967669

SCHEMBL23967669

N#Cc1ccc(N(I)c2cccc3c2sc2c(C(F)(F)F)ccc(-c4cc(N(I)c5cccc6c5sc5c(C(F)(F)F)cccc56)ccc4F)c23)cc1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650456 0.86 SLC22A12 (0.33) KIF11
SCHEMBL23967781 0.80 KIF11 (0.33) KIF11
SCHEMBL20650307 0.76
SCHEMBL20649909 0.75 KIF11 (0.31) KIF11
SCHEMBL20650458 0.75 NR1H2 (0.31)
SCHEMBL21020602 0.73 ABCG2 (0.36) KIF11
SCHEMBL20650248 0.72 EPHX2 (0.33)
SCHEMBL20650467 0.72
SCHEMBL20650457 0.71 SMN1; SMN2 (0.30)
SCHEMBL20649856 0.70 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed