SCHEMBL23967781

SCHEMBL23967781

N#Cc1ccc(N(I)c2cccc3c2oc2c(C(F)(F)F)ccc(-c4cc(N(I)c5cccc6c5oc5c(C(F)(F)F)cccc56)ccc4F)c23)cc1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650699 0.85 SLC22A12 (0.33) KIF11
SCHEMBL23967669 0.80 KIF11 (0.33) KIF11
SCHEMBL20650355 0.75 AR (0.34)
SCHEMBL20650451 0.74 KIF11 (0.31) KIF11
SCHEMBL20650710 0.74 NR1H2 (0.31)
SCHEMBL21020296 0.72 ABCG2 (0.36) KIF11
SCHEMBL20650707 0.72 EPHX2 (0.32)
SCHEMBL20650505 0.72 EPHX2 (0.40)
SCHEMBL20650705 0.71 PTGER1 (0.32)
SCHEMBL20650765 0.70 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed