Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RHOA | P61586 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349136 | 0.82 | MAPT (0.39) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL582900 | 0.79 | MAPT (0.39) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL7866089 | 0.79 | TSHR (0.42) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL194466 | 0.79 | TSHR (0.42) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL877587 | 0.77 | TSHR (0.41) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL4675516 | 0.77 | TSHR (0.41) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL8517677 | 0.77 | TSHR (0.41) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL6194635 | 0.77 | TSHR (0.41) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL1433999 | 0.77 | TSHR (0.33) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL10138926 | 0.77 | MAPT (0.34) | TSHRMAPTCACNA1BAPBA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904341-A1 | R-TYPE PYRIDYLOXYCARBOXYLIC ACID, SALT AND ESTER DERIVATIVE THEREOF, AND PREPARATION METHOD THEREFOR, AND HERBICIDAL COMPOSITION AND APPLICATION THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2021-11-03 | — | — | EP | disclosed |