Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RHOA | P61586 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866089 | 0.84 | TSHR (0.42) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL194466 | 0.84 | TSHR (0.42) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL6194635 | 0.82 | TSHR (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL4675516 | 0.82 | TSHR (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL877587 | 0.82 | TSHR (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL463385 | 0.80 | CYP3A4 (0.42) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL4672773 | 0.80 | TSHR (0.40) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL10587973 | 0.80 | TSHR (0.40) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL4673298 | 0.80 | TDP1 (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL8580033 | 0.80 | TSHR (0.40) | TSHRCYP3A4TDP1MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973086-A | INITIATOR COMPRISING CARBANION AND SALT OF PERCHLORIC ACID | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1999-10-26 | — | — | US | disclosed |