SCHEMBL23967774

SCHEMBL23967774

FC(F)(F)Oc1cccc2c1sc1c(I)cccc12

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
SCN9A Q15858 4/20 0.33
MPL P40238 1/20 0.33
EPHX2 P34913 1/20 0.32
CHRNA7 P36544 1/20 0.32
HTR3A P46098 1/20 0.32
TRPA1 O75762 1/20 0.32
GRIA1 P42261 1/20 0.31
CACNG8 Q8WXS5 1/20 0.31
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25871240 0.89 KDM4E (0.41) KDM4ESCN9AMPLEPHX2CHRNA7
SCHEMBL30740989 0.72 SCN9A (0.38) KDM4ESCN9AEPHX2TRPA1
SCHEMBL934639 0.72 SCN9A (0.38) KDM4ESCN9AEPHX2TRPA1
SCHEMBL12480202 0.71 MPL (0.44) KDM4ESCN9AMPLEPHX2TRPA1
SCHEMBL23967775 0.70 KDM4E (0.36) KDM4ESCN9AEPHX2TRPA1GRIA1
SCHEMBL14661385 0.69 NOTUM (0.38) KDM4ESCN9AMPLGRIA1CACNG8
SCHEMBL28059662 0.69 SCN9A (0.35) KDM4ESCN9AMPL
SCHEMBL20417258 0.69 MPL (0.32) MPL
SCHEMBL12777918 0.68 KDM4E (0.37) KDM4ESCN9AMPLTRPA1GRIA1
SCHEMBL19452855 0.68 MPL (0.37) KDM4EMPLEPHX2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed