SCHEMBL23967775

SCHEMBL23967775

FC(F)(F)Oc1cccc2c1oc1c(I)cccc12

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.36
EPHX2 P34913 1/20 0.35
C1R P00736 1/20 0.35
SCN9A Q15858 3/20 0.34
ALDH1A1 P00352 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
DYRK1A Q13627 1/20 0.33
MAPT P10636 1/20 0.33
RPS6KA2 Q15349 1/20 0.32
CNR2 P34972 1/20 0.32
TRPA1 O75762 1/20 0.32
F2RL3 Q96RI0 2/20 0.31
HTR6 P50406 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
MAOA P21397 1/20 0.30
RAB9A P51151 1/20 0.30
GRIA1 P42261 1/20 0.30
CACNG8 Q8WXS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25906281 0.89 KDM4E (0.41) KDM4EEPHX2C1RSCN9AALDH1A1
SCHEMBL21020257 0.80 MCL1 (0.38) KDM4EEPHX2C1RSCN9AALDH1A1
SCHEMBL1539087 0.78 AHR (0.38) C1RDYRK1A
SCHEMBL934639 0.72 SCN9A (0.38) KDM4EEPHX2SCN9AALDH1A1L3MBTL1
SCHEMBL30740989 0.72 SCN9A (0.38) KDM4EEPHX2SCN9AALDH1A1L3MBTL1
SCHEMBL12480202 0.71 MPL (0.44) KDM4EEPHX2SCN9ATRPA1
SCHEMBL23967897 0.71 NPC1 (0.33) NPC1RAB9A
SCHEMBL23967774 0.70 KDM4E (0.36) KDM4EEPHX2SCN9ADYRK1ATRPA1
SCHEMBL28059662 0.69 SCN9A (0.35) KDM4ESCN9AALDH1A1L3MBTL1MAPT
SCHEMBL14661385 0.69 NOTUM (0.38) KDM4ESCN9AL3MBTL1MAPTGRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed