Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740989 | 1.00 | SCN9A (0.38) | SCN9AGAARXRARXRBRXRG | |
| SCHEMBL28777064 | 0.88 | SLC22A12 (0.38) | SCN9AGAARXRARXRBRXRG | |
| SCHEMBL29344589 | 0.84 | FABP7 (0.31) | — | |
| SCHEMBL4654446 | 0.82 | RXRA (0.47) | SCN9AGAARXRARXRBRXRG | |
| SCHEMBL12480202 | 0.80 | MPL (0.44) | SCN9AGAARXRARXRBRXRG | |
| SCHEMBL14661385 | 0.79 | NOTUM (0.38) | SCN9AL3MBTL1KDM4E | |
| SCHEMBL1768429 | 0.78 | SCN9A (0.41) | SCN9AALDH1A1L3MBTL1HSD11B1CYP2D6 | |
| SCHEMBL29344700 | 0.78 | FABP7 (0.33) | — | |
| SCHEMBL2760211 | 0.76 | KCNH2 (0.37) | ALDH1A1KCNH2KDM4E | |
| SCHEMBL23099860 | 0.76 | GPR3 (0.40) | EPHX2SLC6A2SLC6A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963344-A1 | ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS | UNIVERSITEIT GENT (BE) | 2008-09-03 | — | — | EP | claimed |
| WO-2007071453-A1 | ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS | UNIVERSITEIT GENT (BE) | 2007-06-28 | — | — | WO | claimed |
| WO-2025262243-A1 | THIENO- AND THIAZOLOPYRIMIDINE-2,6-DIONES AND USE THEREOF AS IMMUNOMODULATORS | INVIOS GMBH (AT) | 2025-12-26 | — | — | WO | disclosed |
| EP-4602044-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | invIOs GmbH (AT) | 2025-08-20 | — | — | EP | disclosed |
| US-20240287052-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASES COMPRISING THE SAME | AZCURIS CO., LTD. (KR) | 2024-08-29 | — | — | US | disclosed |
| EP-3632910-B1 | 3,4-DIHYDROQUINOLINONES AS FXR RECEPTOR AGONISTS | CSPC ZHONGQI PHARMACEUTICAL TECH SHIJIAZHUANG CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |
| EP-4389749-A1 | SUBSTITUTED 3,7-DIHYDRO-1H-PURINE-2,6-DIONES AND USE THEREOF | invIOs GmbH (AT) | 2024-06-26 | — | — | EP | disclosed |
| US-11999716-B2 | WDR5 inhibitors and modulators | VANDERBILT UNIVERSITY (US) | 2024-06-04 | — | — | US | disclosed |
| EP-4349818-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | Azcuris Co., Ltd. (KR) | 2024-04-10 | — | — | EP | disclosed |
| EP-0891333-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997049710-A1 | SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997036875-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| EP-0244328-B1 | PROCESS FOR THE PREPARATION OF AROMATIC ALDEHYDES | RHONE-POULENC CHIMIE (FR) | 1991-04-10 | — | — | EP | disclosed |
| US-4978801-A | Preparation of aromatic aldehydes | RHONE-POULENC CHIMIE (FR) | 1990-12-18 | — | — | US | disclosed |
| US-4942240-A | REACTION OF HYDROGEN AND CARBON MONOXIDE WITH AN AROMATIC HALIDE IN THE PRESENCE OF A NOBLE METAL CATALYSTS | RHONE-POULENC CHIMIE (FR) | 1990-07-17 | — | — | US | disclosed |
| CN-1032435-A | The phenyl trifluoromethyl ethers that replaces | MERCK PATENT GMBH (DE) | 1989-04-19 | — | — | CN | disclosed |
| EP-0244329-A2 | Process for the preparation of aromatic aldehydes | RHONE-POULENC CHIMIE (FR) | 1987-11-04 | — | — | EP | disclosed |
| EP-0244328-A2 | Process for the preparation of aromatic aldehydes | RHONE-POULENC CHIMIE (FR) | 1987-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11999716-B2 | WDR5 inhibitors and modulators | WDR5, WDR1, WDR3 | SCN9A 3290/4885GAA 3973/4885RXRA 2466/4885 |
| US-20240287052-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASES COMPRISING THE SAME | IL33, TSLP, IL5 | SCN9A 4343/4885GAA 2770/4885RXRA 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.