SCHEMBL23967896

SCHEMBL23967896

CCc1ccc(N(I)c2cccc3c2oc2c(C#N)cccc23)cc1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
CYP2A6 P11509 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21020287 0.86 CYP1A2 (0.37) CYP1A2CYP3A4CYP2D6CYP2C9HPGD
SCHEMBL20649758 0.86 KDM4E (0.35) KDM4EALDH1A1GAAMAPT
SCHEMBL20650765 0.85 KDM4E (0.33) KDM4EALDH1A1GAAMAPT
SCHEMBL20650764 0.83 KDM4E (0.33) KDM4EALDH1A1GAAMAPT
SCHEMBL23967895 0.83 ALDH1A1 (0.36) HPGDKDM4EALDH1A1GAAMAPT
SCHEMBL20649762 0.83 KDM4E (0.33) KDM4EALDH1A1GAAMAPT
SCHEMBL20649838 0.81 TSHR (0.35) KDM4EALDH1A1GAAMAPTSLC6A2
SCHEMBL20650730 0.81 NPC1 (0.32)
SCHEMBL20650761 0.81 ELANE (0.33) CYP3A4KDM4EALDH1A1GAAMAPT
SCHEMBL20650762 0.80 KEAP1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed