Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 10/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.49 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17471213 | 0.87 | PTK6 (0.49) | PTK6ALKERBB2AURKAEGFR | |
| SCHEMBL16257469 | 0.84 | LRRK2 (0.53) | PTK6ALKERBB2AURKAEGFR | |
| SCHEMBL16024050 | 0.82 | MAPK14 (0.45) | PTK6ALKERBB2AURKAEGFR | |
| SCHEMBL16011996 | 0.82 | PTK6 (0.47) | PTK6ALKERBB2AURKAEGFR | |
| SCHEMBL17453379 | 0.81 | UTS2R (0.44) | PTK6ALKERBB2AURKAEGFR | |
| SCHEMBL16024047 | 0.81 | ERBB2 (0.61) | PTK6ALKERBB2AURKAEGFR | |
| SCHEMBL16011993 | 0.81 | MAPK14 (0.48) | PTK6ALKERBB2AURKAEGFR | |
| SCHEMBL23967953 | 0.81 | PRMT6 (0.48) | PTK6ALKERBB2AURKAEGFR | |
| SCHEMBL16024064 | 0.80 | UTS2R (0.47) | PTK6ALKERBB2AURKAEGFR | |
| SCHEMBL16024043 | 0.79 | CYP17A1 (0.49) | PTK6ALKERBB2AURKAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189052-B1 | CAMKII INHIBITORS AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2021-11-03 | — | — | EP | disclosed |