SCHEMBL23968837

SCHEMBL23968837

N#Cc1cc2c(cc1-c1ccc(OC(F)(F)F)cc1)-c1cc(-c3ccc(OC(F)(F)F)cc3)c(C#N)cc1C2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP8 P40818 1/20 0.44
USP7 Q93009 1/20 0.44
KDM5A P29375 1/20 0.40
STS P08842 1/20 0.40
FNTA P49354 6/20 0.39
FNTB P49356 6/20 0.39
PGGT1B P53609 5/20 0.39
LYN P07948 1/20 0.39
RPS6KB1 P23443 1/20 0.39
MARK3 P27448 1/20 0.39
FLT3 P36888 1/20 0.39
GSK3B P49841 1/20 0.39
STK3 Q13188 1/20 0.39
DYRK1A Q13627 1/20 0.39
TAOK1 Q7L7X3 1/20 0.39
AURKB Q96GD4 1/20 0.39
SCN9A Q15858 3/20 0.39
KIF11 P52732 1/20 0.38
CES1 P23141 1/20 0.38
TRPA1 O75762 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21917294 0.82 ALDH1A1 (0.38) KDM5AFNTAFNTBPGGT1BLYN
SCHEMBL23969051 0.82 ALDH1A1 (0.38) KDM5AFNTAFNTBPGGT1BLYN
SCHEMBL23968913 0.81 ALDH1A1 (0.37) KDM5AFNTAFNTBPGGT1BLYN
SCHEMBL23968845 0.81 USP8 (0.47) USP8USP7KDM5ASCN9AKIF11
SCHEMBL23969068 0.80 KDM1A (0.39) KDM5ASTSFNTAFNTBPGGT1B
SCHEMBL23968832 0.79 TOP2A (0.46) SCN9AKIF11CES1SCN5ANOTUM
SCHEMBL20329163 0.75 STS (0.44) KDM5ASTSSCN9ATRPA1SCN5A
SCHEMBL16474788 0.71 KDM4E (0.42) KDM5AFNTAFNTBPGGT1BLYN
SCHEMBL134890 0.71 KDM5A (0.37) KDM5ASTSFNTAFNTBPGGT1B
SCHEMBL12953430 0.70 CYP11B1 (0.51) KIF11PGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11165025-B2 Compound and organic electronic element comprising same LG CHEM, LTD. 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165025-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 USP8 1802/4885USP7 3533/4885KDM5A 1689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.