SCHEMBL23968845

SCHEMBL23968845

N#Cc1cc2c(cc1-c1ccc(C(F)(F)F)cc1)-c1cc(-c3ccc(C(F)(F)F)cc3)c(C#N)cc1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP8 P40818 1/20 0.47
USP7 Q93009 1/20 0.47
KIF11 P52732 4/20 0.47
XDH P47989 1/20 0.44
PTPN5 P54829 1/20 0.41
MAOB P27338 1/20 0.40
CNR1 P21554 1/20 0.40
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALOX5AP P20292 1/20 0.38
FEN1 P39748 1/20 0.38
AR P10275 2/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
SCN9A Q15858 3/20 0.38
SCN5A Q14524 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
KDM5A P29375 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21917103 0.81 KIF11 (0.42) KIF11XDHPTPN5CNR1ALDH1A1
SCHEMBL21917429 0.81 KIF11 (0.42) KIF11XDHPTPN5CNR1ALDH1A1
SCHEMBL23968837 0.81 USP8 (0.44) USP8USP7KIF11XDHMAOB
SCHEMBL29876988 0.78 KIF11 (0.53) KIF11XDHPTPN5ALDH1A1MAPT
SCHEMBL23968981 0.77 KIF11 (0.47) KIF11MAOBAR
SCHEMBL1482792 0.76 APP (0.42) KIF11MAOBALDH1A1MAPT
SCHEMBL12276043 0.74 KIF11 (0.49) KIF11XDHPTPN5ALDH1A1MAPT
SCHEMBL23915974 0.73 KIF11 (0.52) KIF11XDHPTPN5CNR1ALDH1A1
SCHEMBL21917694 0.73 XDH (0.36) KIF11XDHPTPN5MAOBCNR1
SCHEMBL23754252 0.73 XDH (0.50) KIF11XDHPTPN5ARPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11165025-B2 Compound and organic electronic element comprising same LG CHEM, LTD. 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165025-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 USP8 1802/4885USP7 3533/4885KIF11 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.