SCHEMBL23968853

SCHEMBL23968853

N#CC(C#N)=C1c2cc(OC(F)(F)F)c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc2-c2cc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)c(OC(F)(F)F)cc21

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RPS6KA3 P51812 1/20 0.33
JAK3 P52333 1/20 0.33
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.30
CTSA P10619 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23968999 0.92 KDM4E (0.33) KDM4EMAPTL3MBTL1
SCHEMBL21917696 0.92 RXRA (0.37) KDM4EMAPTL3MBTL1RPS6KA3JAK3
SCHEMBL23968819 0.88 BACE1 (0.41) KDM4EMAPTL3MBTL1AKR1C3AKR1C2
SCHEMBL23969088 0.87 KDM4E (0.46) KDM4EMAPTL3MBTL1AKR1C3AKR1C2
SCHEMBL23969000 0.86 RXRA (0.45) KDM4EMAPTL3MBTL1PTGDR2
SCHEMBL21917695 0.84
SCHEMBL12149348 0.84 MAPT (0.36) MAPT
SCHEMBL21917319 0.84 PGR (0.31) PTGDR2
SCHEMBL23968920 0.84
SCHEMBL23969037 0.82 MAPT (0.37) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11165025-B2 Compound and organic electronic element comprising same LG CHEM, LTD. 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165025-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 KDM4E 664/4885MAPT 1908/4885L3MBTL1 3225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.