SCHEMBL23968960

SCHEMBL23968960

N#CC(C#N)=C1c2cc(OC(F)(F)F)c(-c3ccccc3F)cc2-c2cc(-c3ccccc3F)c(OC(F)(F)F)cc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
SCN9A Q15858 4/20 0.32
KCNN4 O15554 1/20 0.32
PDK2 Q15119 2/20 0.32
DHODH Q02127 2/20 0.32
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
PDE2A O00408 1/20 0.32
MAPT P10636 2/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
EPHX2 P34913 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23968956 0.87 PDK2 (0.32) SCN9APDK2ALDH1A1PDE2AMAPT
SCHEMBL23968856 0.85 FFAR4 (0.38) ALDH1A1MEN1KMT2APDE2AMAPT
SCHEMBL21917313 0.84 BACE1 (0.37) SCN9AALDH1A1MAPTGAAPKM
SCHEMBL12149348 0.83 MAPT (0.36) ALDH1A1MEN1KMT2AMAPTGAA
SCHEMBL23969037 0.81 MAPT (0.37) ALDH1A1MEN1KMT2APDE2AMAPT
SCHEMBL23969073 0.81 PDE2A (0.39) SCN9AALDH1A1PDE2AMAPTGAA
SCHEMBL23968957 0.80 PDE3B (0.37) PDK2DHODHALDH1A1MEN1KMT2A
SCHEMBL23968918 0.80
SCHEMBL23968920 0.80
SCHEMBL23968828 0.80 ALDH1A1 (0.31) ALDH1A1MAPTGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11165025-B2 Compound and organic electronic element comprising same LG CHEM, LTD. 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165025-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 TRPA1 54/4885TRPM8 42/4885TRPV1 773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.