SCHEMBL23968856

SCHEMBL23968856

N#CC(C#N)=C1c2cc(OC(F)(F)F)c(-c3ccc(OC(F)(F)F)cc3F)cc2-c2cc(-c3ccc(OC(F)(F)F)cc3F)c(OC(F)(F)F)cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 3/20 0.38
GPR3 P46089 5/20 0.37
ALOX5AP P20292 1/20 0.36
FEN1 P39748 1/20 0.36
ALDH1A1 P00352 3/20 0.34
MAPT P10636 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
BLM P54132 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
EPAS1 Q99814 1/20 0.34
CYP1A2 P05177 2/20 0.34
GAA P10253 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23968960 0.85 TRPA1 (0.33) ALOX5APFEN1ALDH1A1MAPTMEN1
SCHEMBL12148955 0.84 GPR3 (0.44) FFAR4GPR3ALDH1A1MAPTTDP1
SCHEMBL23968861 0.83 ALDH1A1 (0.39) FFAR4ALDH1A1MAPTTDP1MEN1
SCHEMBL21917690 0.82 ALDH1A1 (0.38) FFAR4ALDH1A1MAPTTDP1MEN1
SCHEMBL12149348 0.81 MAPT (0.36) ALDH1A1MAPTTDP1MEN1TP53
SCHEMBL22966179 0.81 GPR3 (0.47) FFAR4GPR3ALDH1A1MAPTTDP1
SCHEMBL23968956 0.80 PDK2 (0.32) ALDH1A1MAPTGAAPKMPDE2A
SCHEMBL23969037 0.79 MAPT (0.37) ALDH1A1MAPTTDP1MEN1TP53
SCHEMBL12149351 0.79 GPR3 (0.41) FFAR4GPR3ALDH1A1MAPTTDP1
SCHEMBL23969073 0.79 PDE2A (0.39) FFAR4ALOX5APFEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11165025-B2 Compound and organic electronic element comprising same LG CHEM, LTD. 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165025-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 FFAR4 4646/4885GPR3 4622/4885ALOX5AP 3064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.