SCHEMBL23968973

SCHEMBL23968973

N#Cc1cc2c(cc1C#N)-c1cc(C#N)c(C#N)cc1C2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP8 P40818 1/20 0.39
USP7 Q93009 1/20 0.39
KDM4E B2RXH2 4/20 0.34
HPGD P15428 3/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
PDE5A O76074 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17954607 0.85 ALDH1A1 (0.48) USP8USP7KDM4EHPGDALDH1A1
SCHEMBL21917666 0.75 ALDH1A1 (0.41) KDM4EHPGDALDH1A1MAPTNPSR1
SCHEMBL23968833 0.72 KCNJ1 (0.40)
SCHEMBL30820066 0.72 USP8 (0.47) USP8USP7KDM4EHPGDALDH1A1
SCHEMBL24121031 0.72 USP8 (0.47) USP8USP7KDM4EHPGDALDH1A1
SCHEMBL28308270 0.70 KDM4E (0.48) KDM4EHPGDALDH1A1MAPTSMN1; SMN2
SCHEMBL11676256 0.70 PNMT (0.47) ALDH1A1HTR2AHTR2CMAOAMAOB
SCHEMBL56906 0.69 USP8 (0.40) USP8USP7KDM4EHPGDALDH1A1
SCHEMBL10049820 0.67 EGFR (0.40) USP8USP7KDM4EALDH1A1MAPT
SCHEMBL15271277 0.67 USP7 (0.71) USP8USP7KDM4EHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11165025-B2 Compound and organic electronic element comprising same LG CHEM, LTD. 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165025-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 USP8 1802/4885USP7 3533/4885KDM4E 664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.