Homatropine

Homatropine

SCHEMBL23969

CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(O)c1ccccc1)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 1.00
CYP2D6 P10635 3/20 1.00
CYP2C9 P11712 1/20 1.00
HSD17B10 Q99714 1/20 1.00
CHRM2 P08172 6/20 0.97
CHRM1 P11229 6/20 0.97
CHRM3 P20309 6/20 0.97
CHRM5 P08912 5/20 0.97
CHRM4 P08173 4/20 0.97
BLM P54132 2/20 0.97
SMN1; SMN2 Q16637 1/20 0.97
TDP1 Q9NUW8 1/20 0.97
HTR2C P28335 3/20 0.70
ADRA2C P18825 2/20 0.70
ADRA1A P35348 2/20 0.70
HRH1 P35367 2/20 0.70
ADRA1D P25100 2/20 0.70
KDM4E B2RXH2 1/20 0.70
MEN1 O00255 1/20 0.70
POLB P06746 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Homatropine SCHEMBL15275620 1.00 LMNA (1.00) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL23468168 1.00 LMNA (1.00) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL9653008 1.00 LMNA (1.00) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL23970 1.00 LMNA (1.00) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL41951 0.99 CHRM2 (1.00) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL41950 0.99 CHRM2 (1.00) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL220965 0.99 LMNA (0.97) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL220964 0.99 LMNA (0.97) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL14672464 0.97 LMNA (0.95) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL10743457 0.97 LMNA (0.95) LMNACYP2D6CYP2C9HSD17B10CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6548 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629360-B2 Ophthalmic composition Sydnexis, Inc. (US) 2026-05-19 US claimed
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
EP-4732755-A2 A SYSTEM FOR AND METHOD OF MONITORING EYE MEDICATION Ocuvation Limited (IE) 2026-04-29 EP claimed
US-20260108150-A1 System For And Method Of Monitoring Eye Medication OCUVATION LTD (IE) 2026-04-23 US claimed
EP-4724079-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2026-04-15 EP claimed
US-20260048096-A1 METHODS AND COMPOSITIONS FOR PRESERVING THE RETINAL OUTER NUCLEAR LAYER (ONL), PHOTORECEPTORS, AND RETINAL THICKNESS STEALTH BIOTHERAPEUTICS INC. (US) 2026-02-19 US claimed
US-12551476-B2 Eye-soothing externally-applied liquid medicine and preparation method therefor Zhang, Boke (US) 2026-02-17 US claimed
US-12544400-B2 Treatment of myopic progression UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2026-02-10 US claimed
EP-4680228-A2 OPHTHALMIC CREAM FORMULATIONS AND THEIR USES Glaukos Corporation (US) 2026-01-21 EP claimed
US-12529704-B2 Methods for objective assessment of stress, early detection of risk for stress disorders, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2026-01-20 US claimed
EP-0126684-A2 Drug delivery system utilizing thermosetting gels MERCK & CO. INC. (US) 1984-11-28 EP claimed
US-4474751-A SUSTAINED RELEASE USING AN ALKYLENEDIAMINE-MODIFIED ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER MERCK & CO., INC. (US) 1984-10-02 US claimed
US-4186184-A Selective administration of drug with ocular therapeutic system ALZA CORPORATION (US) 1980-01-29 US claimed
US-4186185-A Compositions comprising arylene substituted poly(orthoesters) containing useful agents ALZA CORPORATION (US) 1980-01-29 US claimed
US-4115544-A DRUG PARTICLES MIXED WITH RELEASE RATE-CONTROLLING HOMOPOLYMER ALZA CORPORATION (US) 1978-09-19 US claimed
US-4066747-A Polymeric orthoesters housing beneficial drug for controlled release therefrom ALZA CORPORATION (US) 1978-01-03 US claimed
US-4014334-A Laminated osmotic system for dispensing beneficial agent ALZA CORPORATION (US) 1977-03-29 US claimed
US-4014335-A Ocular drug delivery device ALZA CORPORATION (US) 1977-03-29 US claimed
US-4008719-A Osmotic system having laminar arrangement for programming delivery of active agent ALZA CORPORATION (US) 1977-02-22 US claimed
US-4001388-A POLYESTERS ALZA CORPORATION (US) 1977-01-04 US claimed