Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.95 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.95 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.95 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.95 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.92 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.92 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.92 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.92 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.92 |
| ▸ | BLM | P54132 | 2/20 | 0.92 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.92 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.92 |
| ▸ | HTR2C | P28335 | 3/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.67 |
| ▸ | HRH1 | P35367 | 2/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homatropine SCHEMBL77825 | 1.00 | LMNA (0.95) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| Homatropine SCHEMBL9653008 | 0.97 | LMNA (1.00) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| Homatropine SCHEMBL15275620 | 0.97 | LMNA (1.00) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| Homatropine SCHEMBL23969 | 0.97 | LMNA (1.00) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| Homatropine SCHEMBL23970 | 0.97 | LMNA (1.00) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| Homatropine SCHEMBL23468168 | 0.97 | LMNA (1.00) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| Homatropine SCHEMBL41950 | 0.96 | CHRM2 (1.00) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| Homatropine SCHEMBL220964 | 0.96 | LMNA (0.97) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| Homatropine SCHEMBL220965 | 0.96 | LMNA (0.97) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| Homatropine SCHEMBL41951 | 0.96 | CHRM2 (1.00) | LMNACYP2D6CYP2C9HSD17B10CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028628-B | RSV-F protein small molecule inhibitor and application thereof in preparation of medicines for preventing and treating RSV infection | 中南大学 | 2023-10-10 | — | — | CN | claimed |
| EP-4178948-A2 | FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF | Universidade de Santiago de Compostela (ES) | 2023-05-17 | — | — | EP | claimed |
| EP-4154879-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NICOTINE WITHDRAWAL SYMPTOMS | Korea Institute of Science and Technology (KR) | 2023-03-29 | — | — | EP | claimed |
| EP-4088717-A1 | USE AND COMPOSITION FOR TREATING DEMENTIA | Chase Pharmaceuticals Corporation (US) | 2022-11-16 | — | — | EP | claimed |
| WO-2022023496-A2 | FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2022-02-03 | — | — | WO | claimed |
| US-20200397702-A1 | PHARMACEUTICAL COMPOSITIONS | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2020-12-24 | — | — | US | claimed |
| EP-3493789-A2 | INTRANASAL PHARMACEUTICAL POWDER COMPOSITIONS | Shin Nippon Biomedical Laboratories, Ltd. (JP) | 2019-06-12 | — | — | EP | claimed |
| US-20190105404-A1 | INHALANT FORMULATION CONTAINING SULFOALKYL ETHER CYCLODEXTRIN AND CORTICOSTEROID | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2019-04-11 | — | — | US | claimed |
| US-10149822-B2 | Compositions and methods for combination ingredient delivery | THE FIX, LLC (US) | 2018-12-11 | — | — | US | claimed |
| US-10123996-B2 | Macrocyclic lactone compounds and methods for their use | ELIXIR MEDICAL CORPORATION (US) | 2018-11-13 | — | — | US | claimed |
| WO-2005065435-A2 | INHALANT FORMULATION CONTAINING SULFOALKYL ETHER CYCLODEXTRIN AND CORTICOSTEROID | CYDEX, INC. ET AL. (US) | 2005-07-21 | — | — | WO | claimed |
| EP-1480677-A2 | COMPOSITION FOR STABILIZING HYALURONIC ACID | IOLTECH (FR) | 2004-12-01 | — | — | EP | claimed |
| US-20030133986-A1 | Compositions for stabilizing poly (carboxylic acids) | TSAO FU-PAO (US) | 2003-07-17 | — | — | US | claimed |
| WO-2003043660-A2 | COMPOSITION FOR STABILIZING HYALURONIC ACID | NOVARTIS AG (CH) | 2003-05-30 | — | — | WO | claimed |
| EP-1233761-A1 | OSMOTIC DOSAGE FORM COMPRISING FIRST AND SECOND COATS | ALZA Corporation (US) | 2002-08-28 | — | — | EP | claimed |
| WO-2001037815-A1 | OSMOTIC DOSAGE FORM COMPRISING FIRST AND SECOND | ALZA CORPORATION (US) | 2001-05-31 | — | — | WO | claimed |
| US-5008111-A | Pretreating skin with anticholinergic quaternary ammonium salt to suppress perspiration | SCHERING CORPORATION (US) | 1991-04-16 | — | — | US | claimed |
| US-4824676-A | ANTICHOLINERGIC AGENT TO SUPPRESS PERSPIRATION | SCHERING CORPORATION (US) | 1989-04-25 | — | — | US | claimed |
| US-4765985-A | TRANSDERMAL ADMINISTRATION OF PYROLO(2,3-B)INDOLE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1988-08-23 | — | — | US | claimed |
| US-4680172-A | ARECOLINE AND DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1987-07-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10123996-B2 | Macrocyclic lactone compounds and methods for their use | CHRM2, CHRM1, CHRM5 | LMNA 1791/4885CYP2D6 13/4885CYP2C9 103/4885 |
| US-20190105404-A1 | INHALANT FORMULATION CONTAINING SULFOALKYL ETHER CYCLODEXTRIN AND CORTICOSTEROID | STS, SAE1, PDCD2L | LMNA 4207/4885CYP2D6 125/4885CYP2C9 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.