SCHEMBL23969013

SCHEMBL23969013

N#CC(C#N)=C1c2cc(C#N)c(-c3cc(F)c(F)c(C(F)(F)F)c3)cc2-c2cc(-c3cc(F)c(F)c(C(F)(F)F)c3)c(C#N)cc21

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AR P10275 14/20 0.36
PGR P06401 3/20 0.36
KIF11 P52732 1/20 0.34
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21917307 1.00 AR (0.36) ARPGRKIF11RXRARXRB
SCHEMBL21917303 0.88 ALDH1A1 (0.33)
SCHEMBL21917092 0.88 ALDH1A1 (0.33)
SCHEMBL21917133 0.88 AR (0.35) ARPGRKIF11RXRARXRB
SCHEMBL23969011 0.85 CYP11B1 (0.32) ARPGRKIF11CYP11B1CYP11B2
SCHEMBL21917121 0.85 CYP11B1 (0.32) ARPGRKIF11CYP11B1CYP11B2
SCHEMBL21917136 0.85 ESR1 (0.33) CYP11B1CYP11B2
SCHEMBL23969086 0.85 AR (0.44) ARPGRKIF11RXRARXRB
SCHEMBL21917130 0.85 KIF11 (0.49) ARPGRKIF11CYP11B1CYP11B2
SCHEMBL12198223 0.82 KIF11 (0.40) ARPGRKIF11RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11165025-B2 Compound and organic electronic element comprising same LG CHEM, LTD. 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165025-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 AR 725/4885PGR 1154/4885KIF11 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.