Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ4 | P56696 | 4/20 | 0.56 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18600341 | 0.84 | KCNQ4 (0.55) | KCNQ4KCNQ2KCNQ5CYP1A2CYP2C8 | |
| SCHEMBL18600344 | 0.83 | KCNQ4 (0.60) | KCNQ4KCNQ2KCNQ5CYP1A2CYP2C8 | |
| SCHEMBL18600345 | 0.83 | CYP1A2 (0.59) | KCNQ4KCNQ2KCNQ5CYP1A2CYP2C8 | |
| SCHEMBL18575369 | 0.83 | ALDH1A1 (0.61) | KCNQ4KCNQ2KCNQ5CYP1A2CYP2C8 | |
| SCHEMBL18600342 | 0.82 | KCNQ4 (0.53) | KCNQ4KCNQ2KCNQ5CYP1A2CYP2C8 | |
| SCHEMBL30494445 | 0.82 | KCNQ4 (0.60) | KCNQ4KCNQ2KCNQ5CYP1A2CYP2C8 | |
| SCHEMBL15996890 | 0.81 | CYP1A2 (0.72) | KCNQ4KCNQ2KCNQ5CYP1A2CYP2C8 | |
| SCHEMBL15996884 | 0.81 | KCNQ4 (0.78) | KCNQ4KCNQ2KCNQ5CYP1A2CYP2C8 | |
| SCHEMBL20159076 | 0.81 | KCNQ4 (0.56) | KCNQ4KCNQ2KCNQ5CYP1A2CYP2C8 | |
| SCHEMBL15997126 | 0.79 | KCNQ4 (0.53) | KCNQ4KCNQ2KCNQ5CYP1A2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3138833-B1 | NOVEL KCNQ POTASSIUM CHANNEL AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2021-11-03 | — | — | EP | disclosed |