Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30731584 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HPGDL3MBTL1HDAC8HDAC3 | |
| SCHEMBL28693655 | 0.98 | ALDH1A1 (0.47) | ALDH1A1HPGDL3MBTL1HDAC8HDAC3 | |
| SCHEMBL29732735 | 0.94 | ALDH1A1 (0.46) | ALDH1A1HPGDL3MBTL1HDAC8HDAC3 | |
| SCHEMBL23969591 | 0.94 | ALDH1A1 (0.46) | ALDH1A1HPGDL3MBTL1HDAC8HDAC3 | |
| SCHEMBL8378082 | 0.94 | ALDH1A1 (0.46) | ALDH1A1HPGDL3MBTL1HDAC8HDAC3 | |
| SCHEMBL3679722 | 0.92 | ASAH1 (0.50) | ALDH1A1HPGDL3MBTL1KMT2AMEN1 | |
| SCHEMBL3678799 | 0.92 | ASAH1 (0.50) | ALDH1A1HPGDL3MBTL1KMT2AMEN1 | |
| SCHEMBL3678825 | 0.92 | ASAH1 (0.50) | ALDH1A1HPGDL3MBTL1KMT2AMEN1 | |
| SCHEMBL1537374 | 0.92 | ASAH1 (0.50) | ALDH1A1HPGDL3MBTL1KMT2AMEN1 | |
| SCHEMBL3441079 | 0.92 | ALDH1A1 (0.45) | ALDH1A1HPGDL3MBTL1HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799193-B | Copper and nickel catalyzed decarboxylation borylation | 斯克利普斯研究院 | 2023-12-12 | — | — | CN | disclosed |
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2022-01-27 | — | — | US | disclosed |
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | PCSK9, LIPA, ACSL3 | ALDH1A1 3656/4885HPGD 1472/4885L3MBTL1 1674/4885 |
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | PCSK9, PCSK7, PCSK6 | ALDH1A1 3619/4885HPGD 1376/4885L3MBTL1 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.