Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.44 |
| ▸ | LAP3 | P28838 | 3/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969594 | 1.00 | ANPEP (0.44) | ANPEPLAP3ELANE | |
| SCHEMBL8769600 | 0.71 | ANPEP (0.39) | ANPEPLAP3ELANE | |
| SCHEMBL7437768 | 0.69 | ANPEP (0.50) | ANPEPLAP3 | |
| SCHEMBL19723818 | 0.68 | ANPEP (0.52) | ANPEPLAP3 | |
| SCHEMBL20510142 | 0.67 | ANPEP (0.35) | ANPEPLAP3 | |
| SCHEMBL20510143 | 0.67 | ANPEP (0.35) | ANPEPLAP3 | |
| SCHEMBL23969644 | 0.67 | ANPEP (0.35) | ANPEPLAP3 | |
| SCHEMBL24526101 | 0.67 | ANPEP (0.55) | ANPEPLAP3 | |
| SCHEMBL16526079 | 0.67 | ANPEP (0.55) | ANPEPLAP3 | |
| SCHEMBL23969659 | 0.67 | ANPEP (0.55) | ANPEPLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2022-01-27 | — | — | US | disclosed |
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | PCSK9, LIPA, ACSL3 | ANPEP 346/4885LAP3 142/4885ELANE 493/4885 |
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | PCSK9, PCSK7, PCSK6 | ANPEP 344/4885LAP3 242/4885ELANE 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.