Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824092 | 0.79 | GAA (0.37) | SMN1; SMN2HPGDRAB9APOLBLMNA | |
| SCHEMBL28824060 | 0.78 | MAPT (0.40) | SMN1; SMN2L3MBTL1POLBLMNAHTT | |
| SCHEMBL911477 | 0.77 | GAA (0.36) | SMN1; SMN2HPGDRAB9ANPC1L3MBTL1 | |
| Alcohol SCHEMBL27290979 | 0.73 | GLA (0.36) | HPGDRAB9ANPC1L3MBTL1POLB | |
| SCHEMBL27823976 | 0.73 | NPSR1 (0.41) | SMN1; SMN2IDO1LMNAHTTNOS3 | |
| SCHEMBL3769642 | 0.68 | TYR (0.44) | HPGDIDO1LMNAHTTTYR | |
| Ether SCHEMBL11335812 | 0.67 | ESR1 (0.50) | SMN1; SMN2IDO1LMNAHTTTYR | |
| SCHEMBL19309188 | 0.67 | EPHX1 (0.45) | EPHX1SMN1; SMN2HPGDIDO1RAB9A | |
| Hydrogen Peroxide SCHEMBL182135 | 0.67 | TYR (0.55) | SMN1; SMN2IDO1LMNAHTTTYR | |
| Hydrogen Peroxide SCHEMBL20915049 | 0.67 | TYR (0.55) | SMN1; SMN2IDO1LMNAHTTTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |