SCHEMBL28824092

SCHEMBL28824092

CCOP(O)c1ccc(C)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HTT P42858 2/20 0.37
POLB P06746 2/20 0.37
RAB9A P51151 1/20 0.37
DHODH Q02127 1/20 0.36
ACHE P22303 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 2/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32
AURKA O14965 1/20 0.32
NTRK1 P04629 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28824060 0.81 MAPT (0.40) GAASMN1; SMN2HTTPOLBACHE
SCHEMBL911477 0.80 GAA (0.36) GAASMN1; SMN2POLBRAB9ATDP1
SCHEMBL23969688 0.79 EPHX1 (0.40) SMN1; SMN2HTTPOLBRAB9ALMNA
SCHEMBL13992853 0.79 CA12 (0.44) GAASMN1; SMN2RAB9AACHETDP1
SCHEMBL10709571 0.77 ACHE (0.38) GAASMN1; SMN2HTTDHODHACHE
SCHEMBL6867317 0.77 ACHE (0.38) GAASMN1; SMN2HTTDHODHACHE
Alcohol SCHEMBL27290979 0.77 GLA (0.36) GAAPOLBRAB9ATDP1ALDH1A1
SCHEMBL10439916 0.74 ACHE (0.35) GAASMN1; SMN2HTTACHETDP1
SCHEMBL3818758 0.68 ACHE (0.50) SMN1; SMN2HTTPOLBACHETDP1
SCHEMBL2971551 0.68 ACHE (0.50) SMN1; SMN2HTTPOLBACHETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956979-A Catalyst system for synthesizing phenylacetic acid from toluene 中国科学技术大学 2022-08-30 CN disclosed