Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845823 | 0.82 | KDM4E (0.56) | ALDH1A1MAPK1POLBMEN1KMT2A | |
| SCHEMBL17859661 | 0.70 | KDM4E (0.49) | TSHRALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL17859685 | 0.67 | HPGD (0.55) | TSHRALDH1A1MAPK1NPSR1HPGD | |
| SCHEMBL18834052 | 0.63 | ATM (0.72) | TSHRALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL17522955 | 0.62 | TSHR (0.67) | TSHRALDH1A1MAPK1POLBSIRT5 | |
| SCHEMBL27411452 | 0.62 | ALDH1A1 (0.67) | TSHRALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL15924451 | 0.62 | KMT2A (0.58) | TSHRALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL17845827 | 0.62 | RECQL (0.67) | TSHRALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL6348692 | 0.62 | BRAF (0.72) | TSHRALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL20652970 | 0.61 | ATM (0.62) | TSHRALDH1A1MAPK1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |