Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24599603 | 0.86 | ALDH1A1 (0.33) | ALDH1A1GAAMAPT | |
| SCHEMBL23867814 | 0.81 | — | — | |
| SCHEMBL23969790 | 0.81 | — | — | |
| SCHEMBL23848391 | 0.80 | ALDH1A1 (0.31) | ALDH1A1GAAMAPT | |
| SCHEMBL23848382 | 0.80 | — | — | |
| SCHEMBL23848389 | 0.80 | ALDH1A1 (0.31) | ALDH1A1GAAMAPT | |
| SCHEMBL23569166 | 0.80 | — | — | |
| SCHEMBL23848380 | 0.79 | — | — | |
| SCHEMBL23867678 | 0.76 | — | — | |
| SCHEMBL28424298 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787811-B2 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-10-17 | — | — | US | disclosed |
| US-20230011726-A1 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2023-01-12 | — | — | US | disclosed |
| US-11384087-B1 | — | — | 2022-07-12 | — | — | US | disclosed |
| US-20220213109-A1 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2022-07-07 | — | — | US | disclosed |
| US-11345701-B1 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-05-31 | — | — | US | disclosed |
| US-11161847-B2 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161847-B2 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | ALDH1A1 3827/4885GAA 2707/4885MAPT 2468/4885 |
| US-20230011726-A1 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | ALDH1A1 3978/4885GAA 2859/4885MAPT 2472/4885 |
| US-11384087-B1 | — | KRAS, NRAS, APC | ALDH1A1 3682/4885GAA 2346/4885MAPT 2730/4885 |
| US-11345701-B1 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | ALDH1A1 3827/4885GAA 2707/4885MAPT 2468/4885 |
| US-11787811-B2 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | ALDH1A1 3978/4885GAA 2859/4885MAPT 2472/4885 |
| US-20220213109-A1 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | ALDH1A1 3978/4885GAA 2859/4885MAPT 2472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.