Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851102 | 1.00 | SLC6A2 (0.31) | SLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL23181764 | 0.84 | SLC6A2 (0.31) | SLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL26000644 | 0.75 | — | — | |
| SCHEMBL15934225 | 0.75 | — | — | |
| SCHEMBL31664985 | 0.75 | — | — | |
| SCHEMBL24098322 | 0.75 | L3MBTL1 (0.40) | SLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL23181763 | 0.74 | PNMT (0.35) | — | |
| Hydrochloric Acid SCHEMBL18226410 | 0.73 | — | — | |
| SCHEMBL8235199 | 0.72 | L3MBTL1 (0.52) | SLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL26617116 | 0.72 | L3MBTL1 (0.52) | SLC6A2ADRA1AHTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222353-A1 | MACROCYCLIC INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |