SCHEMBL2397201

SCHEMBL2397201

CC(=O)O[C@]1(O)CC[C@]2(C)[C@H]3CC=C4[C@@H]5CC(C)(C)CC[C@]5(C(=O)O)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 11/20 0.68
PTPN2 P17706 6/20 0.68
POLB P06746 3/20 0.68
AKR1B10 O60218 3/20 0.68
GPBAR1 Q8TDU6 3/20 0.68
F3 P13726 3/20 0.68
PSMB11 A5LHX3 2/20 0.68
PSMA7 O14818 2/20 0.68
PLA2G1B P04054 2/20 0.68
PTPRC P08575 2/20 0.68
PTPRF P10586 2/20 0.68
PSMB1 P20618 2/20 0.68
CES1 P23141 2/20 0.68
ACP1 P24666 2/20 0.68
PSMA1 P25786 2/20 0.68
PSMA2 P25787 2/20 0.68
PSMA3 P25788 2/20 0.68
PSMA4 P25789 2/20 0.68
PSMB8 P28062 2/20 0.68
PSMB9 P28065 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5799296 0.87 PTPN1 (0.73) PTPN1PTPN2POLBAKR1B10GPBAR1
SCHEMBL2586364 0.87 PTPN1 (0.73) PTPN1PTPN2POLBAKR1B10GPBAR1
SCHEMBL381229 0.86 PTPN1 (0.69) PTPN1PTPN2POLBAKR1B10GPBAR1
SCHEMBL12274498 0.84 PTPN1 (0.71) PTPN1PTPN2POLBAKR1B10GPBAR1
SCHEMBL5795816 0.83 PTPN1 (0.72) PTPN1PTPN2POLBAKR1B10GPBAR1
SCHEMBL5799434 0.83 PTPN1 (0.72) PTPN1PTPN2POLBAKR1B10GPBAR1
SCHEMBL5799378 0.83 PTPN1 (0.72) PTPN1PTPN2POLBAKR1B10GPBAR1
Gypsogenin SCHEMBL29722834 0.82 PTPN1 (0.83) PTPN1PTPN2POLBAKR1B10GPBAR1
SCHEMBL5797472 0.82 PTPN1 (0.72) PTPN1PTPN2POLBAKR1B10GPBAR1
Oleanolic_Acid SCHEMBL13728119 0.81 PTPN1 (0.96) PTPN1PTPN2POLBAKR1B10GPBAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116942708-A Processing method of fresh Phellinus linteus 南阳师范学院 2023-10-27 CN claimed
EP-2012795-A4 THERAPEUTIC TRITERPENOIDS UNIV MINNESOTA (US) 2009-07-22 EP claimed
US-20090136566-A1 THERAPEUTIC TRITERPENOIDS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2009-05-28 US claimed
EP-2012795-A2 THERAPEUTIC TRITERPENOIDS Regents of the University of Minnesota (US) 2009-01-14 EP claimed
WO-2007121352-A2 THERAPEUTIC TRITERPENOIDS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2007-10-25 WO claimed
CN-116942708-A Processing method of fresh Phellinus linteus 南阳师范学院 2023-10-27 CN disclosed
EP-2823819-B1 OLEANOLIC ACID ACETATE AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING TLR- OR IL-6-MEDIATED DISEASES KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR) 2021-06-02 EP disclosed
US-20110218143-A1 COMPOSITIONS AND METHODS FOR TISSUE REPAIR UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2011-09-08 US disclosed
CN-101810686-A Compatible composition for treating rheumatoid arthritis and preparation method thereof NINGBO LIWAH PLANT 2010-08-25 CN disclosed
EP-2012795-A4 THERAPEUTIC TRITERPENOIDS UNIV MINNESOTA (US) 2009-07-22 EP disclosed
US-20090136566-A1 THERAPEUTIC TRITERPENOIDS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2009-05-28 US disclosed
EP-2012795-A2 THERAPEUTIC TRITERPENOIDS Regents of the University of Minnesota (US) 2009-01-14 EP disclosed
WO-2007121352-A2 THERAPEUTIC TRITERPENOIDS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2007-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090136566-A1 THERAPEUTIC TRITERPENOIDS EBP, PGGT1B, LIPC PTPN1 3600/4885PTPN2 2899/4885POLB 1710/4885
US-20110218143-A1 COMPOSITIONS AND METHODS FOR TISSUE REPAIR CD68, TNNC1, MATR3 PTPN1 2626/4885PTPN2 2565/4885POLB 866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.