Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | LIPE | Q05469 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26027797 | 0.88 | KMT2A (0.54) | HRH3RAB9AKMT2AMEN1MAPT | |
| SCHEMBL13838899 | 0.85 | HPGD (0.59) | HRH3RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL26027577 | 0.85 | HRH3 (0.53) | HRH3RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL3132249 | 0.84 | SMN1; SMN2 (0.54) | HRH3RAB9AALDH1A1MAPTNPC1 | |
| SCHEMBL26713940 | 0.84 | HRH3 (0.49) | HRH3RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL13838900 | 0.78 | HPGD (0.61) | HRH3RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL26184739 | 0.78 | RAB9A (0.48) | HRH3LIPERAB9AALDH1A1KMT2A | |
| SCHEMBL13838915 | 0.77 | HRH3 (0.46) | HRH3ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL23973025 | 0.77 | HRH3 (0.44) | HRH3TPSAB1 | |
| SCHEMBL25668719 | 0.76 | GAA (0.62) | RAB9AALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183415-A1 | TRPV4 INHIBITOR AS THERAPEUTIC DRUG FOR EYE DISEASE | RaQualia Pharma Inc. (JP) | 2023-05-24 | — | — | EP | disclosed |
| WO-2021221169-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2021-11-04 | — | — | WO | disclosed |