Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23972318 | 0.88 | HRH3 (0.52) | KMT2ANPC1RAB9AHRH3SMN1; SMN2 | |
| SCHEMBL13838899 | 0.85 | HPGD (0.59) | KMT2ANPC1RAB9AHRH3SMN1; SMN2 | |
| SCHEMBL26027577 | 0.85 | HRH3 (0.53) | KMT2ANPC1RAB9AHRH3SMN1; SMN2 | |
| SCHEMBL3132249 | 0.84 | SMN1; SMN2 (0.54) | NPC1RAB9AHRH3SMN1; SMN2KCNH2 | |
| SCHEMBL26713940 | 0.84 | HRH3 (0.49) | KMT2ARAB9AHRH3SMN1; SMN2TPSAB1 | |
| SCHEMBL13838900 | 0.78 | HPGD (0.61) | KMT2ANPC1RAB9AHRH3SMN1; SMN2 | |
| SCHEMBL13838915 | 0.77 | HRH3 (0.46) | KMT2AHRH3SMN1; SMN2KCNH2MEN1 | |
| SCHEMBL23973025 | 0.77 | HRH3 (0.44) | HRH3TPSAB1 | |
| SCHEMBL3809234 | 0.74 | HSD11B1 (0.51) | HRH3KCNH2 | |
| SCHEMBL13838919 | 0.74 | HRH3 (0.41) | KMT2AHRH3KCNH2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255965-A1 | TRPV4 INHIBITOR AS A THERAPEUTIC AGENT FOR OCULAR DISEASES | RAQUALIA PHARMA INC. (JP) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255965-A1 | TRPV4 INHIBITOR AS A THERAPEUTIC AGENT FOR OCULAR DISEASES | TRPV4, TRPV5, TRPV2 | KMT2A 2654/4885NPC1 464/4885RAB9A 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.