SCHEMBL2397247

SCHEMBL2397247

O=C(O)CCc1ccc(F)cc1F

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 14/20 0.59
FFAR4 Q5NUL3 12/20 0.59
POLB P06746 1/20 0.51
NPSR1 Q6W5P4 1/20 0.47
TSPO P30536 1/20 0.47
DRD3 P35462 1/20 0.47
MAOB P27338 1/20 0.46
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
RXRG P48443 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30637597 1.00 FFAR1 (0.59) FFAR1FFAR4POLBNPSR1TSPO
Hydrochloric Acid SCHEMBL30461911 0.98 FFAR1 (0.58) FFAR1FFAR4POLBNPSR1TSPO
SCHEMBL6956901 0.91 FFAR1 (0.50) FFAR1FFAR4MAOBHTR2AHTR2C
SCHEMBL15808566 0.87 F13A1 (0.53) FFAR1FFAR4MAOBHTR2AHTR2C
SCHEMBL3576683 0.86 MAOB (0.47) FFAR1FFAR4MAOBHTR2AHTR2C
SCHEMBL29009751 0.86 F13A1 (0.56) FFAR1FFAR4MAOBHTR2AHTR2C
SCHEMBL10277328 0.86 F13A1 (0.56) FFAR1FFAR4MAOBHTR2AHTR2C
SCHEMBL4872028 0.85 POLB (0.60) FFAR1FFAR4POLBNPSR1
SCHEMBL1478187 0.85 FFAR1 (0.51) FFAR1FFAR4POLBNPSR1
SCHEMBL7014207 0.84 MIF (0.52) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143097-A Beta-carbopol compound, preparation method thereof and application of beta-carbopol compound in resisting Alzheimer disease 中国人民解放军北部战区总医院 2023-12-01 CN claimed
EP-4743175-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Aconcagua Bio, Inc. (US) 2026-05-20 EP disclosed
EP-4626876-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-10-08 EP disclosed
US-12404265-B2 Substituted pyridine derivatives as SARM1 inhibitors NURA BIO, INC. (US) 2025-09-02 US disclosed
US-20250051355-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO, INC. 2025-02-13 US disclosed
WO-2025015269-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO, INC. (US) 2025-01-16 WO disclosed
WO-2024115509-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-06 WO disclosed
US-11970481-B1 Substituted pyridine derivatives as SARM1 inhibitors NURA BIO, INC. (US) 2024-04-30 US disclosed
US-20240116901-A1 SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS NURA BIO, INC. 2024-04-11 US disclosed
CN-117143097-A Beta-carbopol compound, preparation method thereof and application of beta-carbopol compound in resisting Alzheimer disease 中国人民解放军北部战区总医院 2023-12-01 CN disclosed
CN-1044811-C Pyrrolopyridazine derivatives SANKYO CO (JP) 1999-08-25 CN disclosed
US-5872118-A RELAXATION OF SKELETAL MUSCLE IN SPASTIC, HYPERTONIC AND HYPERKINETIC CONDITIONS GLAXO WELLCOME INC. (US) 1999-02-16 US disclosed
EP-0742218-A1 PYRROLOPYRIDAZINE DERIVATIVE SANKYO COMPANY LIMITED (JP) 1996-11-13 EP disclosed
EP-0699180-A1 BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS THE WELLCOME FOUNDATION LIMITED (GB) 1996-03-06 EP disclosed
EP-0401166-B1 Nitrogen-containing titanocenes and their use CIBA GEIGY AG (CH) 1995-02-22 EP disclosed
WO-1994026693-A1 BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS THE WELLCOME FOUNDATION LIMITED (GB) 1994-11-24 WO disclosed
WO-1994026692-A1 BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS THE WELLCOME FOUNDATION LIMITED (GB) 1994-11-24 WO disclosed
EP-0553107-A1 PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY PROCYON PHARMACEUTICALS, INC. (US) 1993-08-04 EP disclosed
US-5068371-A Photoinitiators for polymerization CIBA-GEIGY CORPORATION (US) 1991-11-26 US disclosed
EP-0401166-A2 Nitrogen-containing titanocenes and their use CIBA-GEIGY AG (CH) 1990-12-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404265-B2 Substituted pyridine derivatives as SARM1 inhibitors SARM1, SARNP, ADRM1 FFAR1 4246/4885FFAR4 4580/4885POLB 2207/4885
US-11970481-B1 Substituted pyridine derivatives as SARM1 inhibitors SARM1, SARNP, ADRM1 FFAR1 4246/4885FFAR4 4580/4885POLB 2207/4885
US-20240116901-A1 SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS SARM1, SARNP, ADRM1 FFAR1 4246/4885FFAR4 4580/4885POLB 2207/4885
US-20250051355-A1 COMPOUNDS, COMPOSITIONS, AND METHODS IAPP, GIPR, GPR119 FFAR1 190/4885FFAR4 271/4885POLB 4283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.