Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | MGLL | Q99685 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435588 | 0.88 | FAAH (0.45) | FAAHMGLLLMNAKDM4EALDH1A1 | |
| SCHEMBL2217546 | 0.85 | FAAH (0.43) | FAAHMGLLLMNAKDM4EALDH1A1 | |
| SCHEMBL2293707 | 0.85 | FAAH (0.43) | FAAHMGLLLMNAKDM4EALDH1A1 | |
| SCHEMBL2295830 | 0.85 | FAAH (0.43) | FAAHMGLLLMNAKDM4EALDH1A1 | |
| SCHEMBL9996736 | 0.85 | FAAH (0.45) | FAAHMGLLLMNAKDM4EALDH1A1 | |
| SCHEMBL7012103 | 0.84 | FAAH (0.44) | FAAHMGLLLMNAALDH1A1GAA | |
| SCHEMBL12435616 | 0.84 | HPSE (0.45) | FAAHMGLLLMNAKDM4EALDH1A1 | |
| SCHEMBL2217398 | 0.84 | HPSE (0.45) | FAAHMGLLLMNAKDM4EALDH1A1 | |
| SCHEMBL20489265 | 0.84 | HPSE (0.53) | FAAHMGLLLMNAMEN1KMT2A | |
| SCHEMBL20489267 | 0.84 | HPSE (0.53) | FAAHMGLLLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222767-A1 | CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS | GLYCOMIMETICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |