Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | MGLL | Q99685 | 4/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2217398 | 0.96 | HPSE (0.45) | FAAHMGLLHPSELMNAPOLB | |
| SCHEMBL12435616 | 0.96 | HPSE (0.45) | FAAHMGLLHPSELMNAPOLB | |
| SCHEMBL20489267 | 0.90 | HPSE (0.53) | FAAHMGLLHPSELMNAMEN1 | |
| SCHEMBL20489265 | 0.90 | HPSE (0.53) | FAAHMGLLHPSELMNAMEN1 | |
| SCHEMBL12435588 | 0.88 | FAAH (0.45) | FAAHMGLLLMNAPOLBSMN1; SMN2 | |
| SCHEMBL23154564 | 0.86 | LMNA (0.38) | FAAHMGLLHPSELMNAPOLB | |
| SCHEMBL2293707 | 0.85 | FAAH (0.43) | FAAHMGLLLMNAPOLBSMN1; SMN2 | |
| SCHEMBL23974808 | 0.85 | FAAH (0.49) | FAAHMGLLLMNAPOLBSMN1; SMN2 | |
| SCHEMBL2295830 | 0.85 | FAAH (0.43) | FAAHMGLLLMNAPOLBALDH1A1 | |
| SCHEMBL7012103 | 0.84 | FAAH (0.44) | FAAHMGLLLMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | ETH ZURICH (CH) | 2011-07-21 | — | — | US | disclosed |
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | ETH ZURICH (CH) | 2011-07-21 | — | — | US | disclosed |
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | ETH ZURICH (CH) | 2011-07-21 | — | — | US | disclosed |
| WO-2010136539-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | COVALX AG (CH) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010136539-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | COVALX AG (CH) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | MTCL3, BICRA, HMGB3 | FAAH 2750/4885MGLL 4839/4885HPSE 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.