Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649907 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1CTSLSLC15A1 | |
| SCHEMBL627617 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1CTSLSLC15A1 | |
| SCHEMBL28156051 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1CTSLSLC15A1 | |
| SCHEMBL22273544 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL28113865 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1CTSLSLC15A1 | |
| SCHEMBL13764234 | 0.86 | SLC15A1 (0.52) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL22390720 | 0.86 | SLC15A1 (0.52) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL27481185 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL28740804 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL22273744 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021220061-A2 | HETERODIMER COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | RIPPLE THERAPEUTICS CORPORATION (CA) | 2021-11-04 | — | — | WO | disclosed |
| CN-1187360-C | Phosphonic acid derivs, having carboxypeptidase B inhibitory activity | MEIJI SEIKA KAISHA (JP) | 2005-02-02 | — | — | CN | disclosed |
| CN-1373766-A | Phosphonic acid derivatives having carboxypeptidase B inhibitory activity | MEIJI SEIKA KAISHA (JP) | 2002-10-09 | — | — | CN | disclosed |