SCHEMBL23975326

SCHEMBL23975326

CC(C)(C)OC(=O)Cn1ccnc1CN(Cc1nccn1CC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 6/20 0.41
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
HDAC6 Q9UBN7 2/20 0.35
LMNA P02545 1/20 0.35
ALPG P10696 2/20 0.34
PLAA Q9Y263 1/20 0.34
CCNE2 O96020 1/20 0.34
CCNE1 P24864 1/20 0.34
CDK2 P24941 1/20 0.34
ALPL P05186 1/20 0.33
AKT1 P31749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11930749 0.85 FPR2 (0.42) FPR2KDM4EALDH1A1OPRD1OPRK1
SCHEMBL21247638 0.85 FPR2 (0.40) FPR2KDM4EALDH1A1OPRD1OPRK1
SCHEMBL11930753 0.82 FPR2 (0.40) FPR2KDM4EALDH1A1OPRD1OPRK1
SCHEMBL13263679 0.82 ALPG (0.49) FPR2KDM4EALDH1A1HDAC6ALPG
SCHEMBL16607258 0.81 FPR2 (0.43) FPR2ALPGPLAAALPL
SCHEMBL13382073 0.81 FPR2 (0.40) FPR2KDM4EALDH1A1OPRD1OPRK1
SCHEMBL20724674 0.80 FPR2 (0.45) FPR2ALDH1A1ALPGPLAAALPL
SCHEMBL18079522 0.77 FPR2 (0.37) FPR2KDM4EALDH1A1OPRD1OPRK1
SCHEMBL13341514 0.77 CA2 (0.41) FPR2
SCHEMBL28455345 0.77 FPR2 (0.44) FPR2KDM4EALDH1A1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11712485-B2 Triazine based radiopharmaceuticals and radioimaging agents MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2023-08-01 US disclosed
US-20210338850-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2021-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210338850-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS PSMA2, PSMA5, PSMA1 FPR2 2312/4885KDM4E 2245/4885ALDH1A1 2027/4885
US-11712485-B2 Triazine based radiopharmaceuticals and radioimaging agents PSMA2, PSMA5, PSMA1 FPR2 2312/4885KDM4E 2245/4885ALDH1A1 2027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.