Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975465 | 1.00 | TP53 (0.40) | TP53HTTEPHX2CCR1ENPP2 | |
| SCHEMBL23470071 | 0.90 | TP53 (0.52) | TP53EPHX2CCR1ENPP2DPP4 | |
| SCHEMBL23904781 | 0.82 | DPP4 (0.44) | TP53HTTCCR1DPP4ALDH1A1 | |
| SCHEMBL22906848 | 0.81 | MMP2 (0.40) | EPHX2ALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL11937898 | 0.81 | HTT (0.46) | TP53HTTEPHX2CCR1DPP4 | |
| SCHEMBL11937895 | 0.81 | HTT (0.46) | TP53HTTEPHX2CCR1DPP4 | |
| SCHEMBL18754852 | 0.81 | DPP4 (0.43) | DPP4ALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL15840457 | 0.80 | EPHX1 (0.43) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL27437988 | 0.79 | DPP4 (0.41) | DPP4MMP1MMP2MMP3MMP9 | |
| SCHEMBL27375418 | 0.78 | DPP4 (0.41) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021220178-A1 | IAP ANTAGONISTS AND THEIR THERAPEUTIC APPLICATIONS | COMINNEX ZRT. (HU) | 2021-11-04 | — | — | WO | disclosed |