Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21848552 | 0.84 | L3MBTL1 (0.40) | EPHX2HSD11B1UCHL1MEN1KMT2A | |
| SCHEMBL31511192 | 0.83 | EPHX2 (0.48) | EPHX2HSD11B1UCHL1MEN1KMT2A | |
| SCHEMBL23975515 | 0.83 | EPHX2 (0.48) | EPHX2HSD11B1UCHL1MEN1KMT2A | |
| SCHEMBL28459867 | 0.80 | EPHX2 (0.51) | EPHX2HSD11B1UCHL1MEN1KMT2A | |
| SCHEMBL31510905 | 0.80 | EPHX2 (0.51) | EPHX2HSD11B1UCHL1MEN1KMT2A | |
| SCHEMBL30537463 | 0.80 | EPHX2 (0.51) | EPHX2HSD11B1UCHL1MEN1KMT2A | |
| SCHEMBL21848431 | 0.76 | UCHL1 (0.53) | EPHX2UCHL1MEN1KMT2AKLK7 | |
| SCHEMBL22715472 | 0.75 | EPHX2 (0.43) | EPHX2UCHL1MEN1KMT2AKLK7 | |
| SCHEMBL23975412 | 0.73 | UCHL1 (0.44) | EPHX2UCHL1MEN1KMT2AKLK7 | |
| SCHEMBL22892446 | 0.73 | MEN1 (0.50) | EPHX2UCHL1MEN1KMT2AKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021220178-A1 | IAP ANTAGONISTS AND THEIR THERAPEUTIC APPLICATIONS | COMINNEX ZRT. (HU) | 2021-11-04 | — | — | WO | disclosed |