Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 5/20 | 0.35 |
| ▸ | THRB | P10828 | 5/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975552 | 0.88 | ITGB3 (0.38) | ITGB3ITGAVTHRATHRBFFAR1 | |
| SCHEMBL23153245 | 0.86 | ITGB3 (0.42) | ITGB3ITGAVTHRATHRBRXRA | |
| SCHEMBL23153242 | 0.81 | ITGB3 (0.43) | ITGB3ITGAVTHRATHRBRXRA | |
| SCHEMBL23984323 | 0.77 | ITGB3 (0.41) | ITGB3ITGAVTHRATHRBRXRA | |
| SCHEMBL23153285 | 0.76 | ITGB3 (0.39) | ITGB3ITGAVTHRATHRBRXRA | |
| SCHEMBL23153269 | 0.75 | ITGB3 (0.42) | ITGB3ITGAVTHRATHRBRXRA | |
| SCHEMBL23153267 | 0.75 | ITGB3 (0.42) | ITGB3ITGAVTHRATHRBRXRA | |
| SCHEMBL24063205 | 0.71 | ITGB3 (0.35) | ITGB3ITGAVTHRATHRBRXRA | |
| SCHEMBL24063119 | 0.71 | THRB (0.47) | ITGB3ITGAVTHRATHRBFFAR1 | |
| SCHEMBL23984251 | 0.68 | ITGB3 (0.52) | ITGB3ITGAVTHRATHRBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021221836-A1 | COMPOSITION OF SCALABLE THYROINTEGRIN ANTAGONISTS WITH IMPROVED BLOOD BRAIN BARRIER PENETRATION AND RETENTION IN BRAIN TUMORS | NANOPHARMACEUTICALS, LLC (US) | 2021-11-04 | — | — | WO | disclosed |