Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 11/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377748 | 0.87 | MLNR (0.49) | MLNRCYP3A4FAAHKCNH2 | |
| SCHEMBL377854 | 0.84 | MLNR (0.47) | MLNRCYP3A4FAAHRORC | |
| SCHEMBL377818 | 0.82 | MLNR (0.46) | MLNRCYP3A4KCNH2 | |
| SCHEMBL2397561 | 0.79 | MLNR (0.44) | MLNRCYP3A4KCNH2RAB9A | |
| SCHEMBL377498 | 0.79 | MLNR (0.64) | MLNRCYP3A4KCNH2 | |
| SCHEMBL2393780 | 0.78 | FAAH (0.40) | MLNRCYP3A4FAAHRORC | |
| SCHEMBL377770 | 0.78 | CHRM4 (0.42) | MLNRFAAHMCHR1SIGMAR1 | |
| SCHEMBL2396382 | 0.78 | MLNR (0.43) | MLNRCYP3A4FAAHRORC | |
| SCHEMBL376913 | 0.78 | MLNR (0.40) | MLNRCYP3A4FAAHKCNH2 | |
| SCHEMBL377719 | 0.78 | MLNR (0.40) | MLNRCYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012981-B2 | Benzylpiperazine derivatives as motilin receptor agonists | GLAXO GROUP LIMITED (GB) | 2011-09-06 | — | — | US | disclosed |